Endocrine Abstracts

Purpose: Denosumab is a monoclonal antibody that prevents osteoclast development. The effect of denosumab in solid organ transplant recipients has been elucidated, but the effect of denosumab in hematopoietic stem cell transplantation recipients has not been studied yet. Thus, the aim of this study was to determine the effectiveness and safety of denosumab in hematopoietic stem cell transplantation recipients.Methods: We retrospectively evaluated 27 pati...

Purpose: The primary aim of this study was to evaluate changes in the diameter and volume of thyroid cancer nodules identified using fine-needle aspiration biopsy (FNAB) or surgery, and to compare the changes in size between thyroid cancer nodules and benign nodules. The secondary aim was to analyze the risk factors associated with thyroid cancer nodule growth.Methods: A total of 96 patients with 102 nodules were enrolled in the cancer group, and 98 pati...

Background: Although sclerostin (SOST) and Dickkopf-related protein 1 (DKK1) are major regulators in bone metabolism, the associations between these soluble Wnt antagonists and osteoporotic fracture (OF) in Asians, who may have distinct biologic characteristics with Caucasians, are inconclusive. Furthermore, there have been no clinical studies separately considering non-vertebral and vertebral fractures in terms of the blood levels of SOST and DKK1.Metho...